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Explore A-Z conditions
Spinal Cord Injuries (SCIs) and Spinal Cord Diseases (SCDs)
Cannabis for Spinal Cord Injuries (SCIs) and Spinal Cord Diseases (SCDs)
SCIs are thought to affect between 10.4 and 83 people per million every year. In North America, about 39 in every million people incur a traumatic SCI each year. Falls and other high impact injuries are common causes of SCIs, but people with arthritis or multiple sclerosis (MS) are also at high risk of SCIs.
Spinal cord diseases (SCDs) can include degenerative disc disease (DDD), Spinocerebellar Ataxia (SCA), spinal stenosis, tumors affecting the spine, and many more. Activation of CB1 receptors is associated with deficits in motor coordination, whereas CB1 receptor antagonists may help prevent and overcome such deficits, restoring balance to the ECS and (quite literally) balance to the body and one’s ability to move.
There are a number of endocannabinoid receptors on the spinal cord. Targeting these could help prevent further cell damage. CBD may help repair broken, fractured and porous bones, as the ECS has been shown to play a role in the regulation of bone metabolism and the formation of bones.
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Animal Study
15
Clinical Meta-analysis
5
Clinical Trial
4
Double Blind Clinical Trial
9
Laboratory Study
2
Meta-analysis
23
Meta-analysis -
1
Total studies
Spinal Cord Injuries (SCIs) and Spinal Cord Diseases (SCDs)
59
Positive
47 studies
80%
Inconclusive
6 studies
10%
Negative
6 studies
10%
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Relevant studies
The information in our comprehensive A to Z encyclopedia comes from real scientific studies.
Uncover the detailed results of these studies and find out how effective medical marijuana is for dozens of conditions.
- A CB2-Selective Cannabinoid Suppresses T-cell Activities and Increases Tregs and IL-10
- Activation of spinal and supraspinal cannabinoid-1 receptors lead to antinociception in a rat model of neuropathic spinal cord injury pain
- Activation of spinal cannabinoid 1 receptors inhibits C-fibre driven hyperexcitable neuronal responses and increases [35S]GTPgammaS binding in the dorsal horn of the spinal cord of noninflamed and inflamed rats
- AM404, an inhibitor of anandamide reuptake decreases Fos-immunoreactivity in the spinal cord of neuropathic rats after non-noxious stimulation
- An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain From Spinal Cord Injury and Disease.