Cannabis for cachexia or wasting syndrome

Cachexia, or wasting syndrome, is a condition that causes extreme weight loss and muscle loss. It usually occurs in people with serious illnesses like:

• Cancer
• Multiple sclerosis (MS)
• Eating disorders like anorexia and bulimia
• AIDS/HIV
• Chronic kidney disease (CKD)
• Heart disease or failure

Medical cannabis may help manage some of the symptoms of cachexia, like loss of appetite, nausea, and pain.

Research on cannabis for cachexia

Research suggests that certain compounds in cannabis, particularly tetrahydrocannabinol (THC), may help stimulate appetite and reduce weight loss in people with cachexia.

Studies have found that THC has appetite-boosting effects. Another study found that dronabinol, an FDA-approved synthetic form of THC, improves appetite in people with HIV/AIDS and cancer, and causes weight gain in people with HIV/AIDS.

Other cannabinoids, such ascannabidiol (CBD), may suppress appetite. Studies on cannabis for cachexia generally show promising results. But more high-quality studies are needed to understand its full potential and long-term effects.

Using cannabis for cachexia

Cannabis may help you with symptoms like:

• Appetite loss
• Nausea
• Fatigue

Talk to your doctor before using cannabis for cachexia, especially if you are taking medication.

Benefits

Cannabis has some potential benefits related to cachexia.

• Increases appetite: THC can boost hunger by stimulating the release of the hunger hormones leptin and ghrelin.
• Reduces nausea: Cannabis may help with nausea so that you can keep food down.
• Eases pain and inflammation: Certain compounds in cannabis, including THC and beta-caryophyllene, may reduce inflammation and pain.

Risks and side effects

As with any medicine, cannabis has potential risks and side effects.

• Drowsiness: Some people feel tired after using cannabis.
• Dizziness: Cannabis can make you feel lightheaded, especially at high doses.
• Mental effects: THC can cause anxiety, paranoia, or memory problems.

Is it legal?

Cannabis laws vary across the U.S. In some states, cachexia is a qualifying condition for a medical cannabis card. In other states, you may qualify through a condition that can lead to cachexia, like HIV/AIDS or cancer.

In some states, you can apply to become a medical cannabis caregiver to a minor with cachexia.

The Food and Drug Administration (FDA) has approved a THC-based drug, dronabinol, for weight loss related to a condition like cancer or AIDS. Dronabinol is only available through prescription.

More about cachexia

About 160,000 people are admitted to hospitals each year for cachexia.

Your doctor can diagnose cachexia through blood tests and by assessing your weight and muscle strength.

People with cachexia may or may not have a lower life expectancy depending on the underlying condition.

Other treatments for cachexia

There is no cure for cachexia. Your doctor will suggest treatments to slow down weight loss and improve symptoms.

Traditional therapies

Standard treatments for cachexia include:

• Nutritional support: High-calorie diets and supplements may help you maintain weight and muscle mass.
• Medications: Medications like megestrol acetate and dronabinol may improve appetite.
• Physical therapy: Certain stretches and exercises may help you maintain muscle strength.

Cannabis as part of your treatment plan for cachexia (wasting syndrome)

Cannabis may help you manage some cachexia symptoms. But it should be part of a broader treatment plan. If you’re considering medical cannabis, talk to your doctor to see if it’s right for you.

In many states, cachexia is a qualifying condition for a medical cannabis card. To start the process of getting your medical card, contact Leafwell today.

Frequently asked questions

Find answers to common questions about medical cannabis and cachexia.

Can cannabis help with weight gain in cachexia?

Yes. THC may boost appetite and increase food intake. However, its effects can vary from person to person and depend on your underlying health condition.

What’s the best way to take cannabis for cachexia?

Popular cannabis product types for cachexia include:

• Smokable flower
• Vaporizers
• Edibles
• Tinctures

The best option depends on your personal preferences and medical needs.

Are there cannabis-based medications for cachexia?

Yes. Dronabinol (Marinol) and nabilone (Cesamet) are FDA-approved THC-based medications prescribed for nausea and low appetite.

Which is better for increasing hunger, CBD or THC?

THC may increase appetite, while CBD may suppress it.

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